Can Botox Cosmetic affect my brain?

I just read in the about how new studies are saying that Botox Cosmetic can affect the brain in mice.  I am freaking out! Is this for real?  I've had a lot of Botox over the past 5+ years...should I stop getting Botox injections?  How do I know if the Botox Cosmetic has affected my brain?  If it has, can I fix it?  Need more info please!

3 answers to “Can Botox Cosmetic affect my brain?”

A: Highly unlikely that Botox can affect the brain

Steven Wallach, MD

It is extremely unlikely that Botox could impact brain function from use on the forehead. The studies that you mention were done in a rodent model.

A: Don't Worry - I inject patients with Botox every day and I get injected every 4 months

David Shafer, MD

The article in the Journal of Neuroscience earlier this year drew great attention to Botox. The most attention was paid by news media outlets sensationalizing the topic and generating fear to help sell their news. The studies were conducted in rodents, not humans. Additionally, the formulation of Botox used... more

A: Unlikely Problem for Humans

Kamran Jafri, MD

Hello Devora, Please be at ease about Botox and your brain! The study you are referring to was Published in the Journal of Neuroscience earlier this year. The study was conducted in Italy and involved scientists injecting Botox into mice and rats by their whiskers and portions of the brain itself... more

Comments

wjbullis
4 posts
13 Oct 2008

The small amounts of Botox Cosmetic injected to treat facial wrinkles and lines reach negligable levels in the bloodstream.  In other words, it has its affect in the location in which it was injected.  The primary affect of Botox Cosmetic is to interfere with the communication between the nerves and the muscles, resulting in a temporary paralysis of the injected muscle.  To date, no scientific studies have shown any systemic effect of Botox Cosmetic used in this way.  And Botox Cosmetic has been subjected to many prospective studies prior to its FDA approval.

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