Can Botox Trigger Trigeminal Neurolgia?

I have had TN to the send and third branch of the nerve, but have thankfully been pain free for 18 months. I would like Botox around the eye and cheek area but am afraid it may trigger the TN? I have heard Botox can help TN but as I would be having it done by a cosmetic surgeon around the eye and cheeck could it have the opposite effect?

Doctor Answers (3)

Will Botox trigger trigeminal neuralgia?


It shouldn't, but unfortunately in medicine there are no guarantees (be wary if any doctor guarantees any result, even a particular response to a medication such as aspirin).  Based on the pharmacology of Botox, I would not expect it from this drug, but the simple act of injecting may be a trigger.

Paoli Facial Plastic Surgeon

Neuralgia and Botox


Treating the musculature around your eyes with cosmetic Botox shouldn't cause any issues and/or flare up with trigeminal neuralgia. If you haven't met with a reputable and well-trained and informed provider to weigh all of your options, that's a good place to start.

Sam Naficy, MD
Seattle Facial Plastic Surgeon
5.0 out of 5 stars 147 reviews

Botox for trigeminal neuralgia


While I don't have any personal experience using Botox to treat TN, there are several articles suggesting that it is beneficial. For that reason I think it is unlikely that cosmetic Botox would make it worse.

Richard Baxter, MD
Seattle Plastic Surgeon
5.0 out of 5 stars 28 reviews

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