There will be no adverse drug interaction with Botox and any antibiotic. Botox works locally at the neuromuscular junctions of the targeted muscles and will not interact with the systemic nitrofurantoin.
Botox Injection on the Forehead and Cystitis. The Doctor Prescribed Nitrofurantoin. Is It Safe to Combine Both?
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Safety of Botox injections with antibiotic treatment
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