Botox & Dysport No Longer Working as Well, Suggestions?

Botox and Dysport no longer effective on brow area. I've used the same doctor for several years; lately, it's not working as well as it used to. Any suggestions?

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5 Doctor Answers | Asked by pastena57

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Xeomin May Be Effective When Botox and Dysport No Longer Work As Well

I have been using Botox for cosmetic reasons since 1991. Since that time, I occasionally encounter a patient who at first responded well to Botox, but after several treatment sessions, no longer responded as well or has not maintained his/her improvement for as long as previously. Some, for example, who in the past may have enjoyed six months of correction were seeing no more than four to eight weeks of results. I have been using Dysport for about ten years already and have seen a... more

Botox and Dysport can give different results as we age

If you are finding that the glabellar muscles between the eyebrows or the crows feet muscles are not being as relaxed with the same number of units of Botox or Dysport, that is not the same as finding that the forehead muscle is drooping more or the upper eyelids are sagging. If it is the former, then you might be developing some resistance to the injections but this is extremely rare. Changing from them to Xeomin may not make a difference as all three are seropyte A botulinum toxin.... more

Botox/dysport not really working anymore

Some patients do build up a tolerance to Botox or dysport. Often switching to the other product helps. Xeomin may be another option.

Steven Wallach, MD

12 reviews

Manhattan Plastic Surgeon

You might be resistant.

Then again, perhaps you just need more treatment than you have had in the past. Occasionally, doctors change precisely how much treatment they are giving. You might try a different office and see if you remain "resistant."

Kenneth D. Steinsapir, MD

8 reviews

Los Angeles Oculoplastic Surgeon

Botox and Dysport Resistance

There is some intolerance built up over time for both Botox and Dysport. Just like with anything, your body will create natural antibodies and so it makes this type of injection either not as effective, or maybe not last as long, or something like that. I haven't seen it happen (yet) with Dysport, but it will. I have experienced it with Botox recipients who've gotten the injections for years and years and years. However, with those patients I've tried to inject Dysport and that... more