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Why Did my Body Metastasize Juvederm Lip Injections So Quickly?

I had Juvederm (1 vial) injected, for the first time, in both my upper and lower lips a little over a month ago. I have lumps on the inside of just my upper lip that I have continued to massage, but they do not appear to go down at all, and even swell more as the day progresses (I'm assuming from water rentention?). In addtion, I feel as if my body has already, I guess, metabolically absorbed the Juverderm, as I am no longer seeing the great results that I did in the beginning. I am healthy, with no immuno-deficiencies, etc. Why did my body absorb the Juvederm so quickly, and why does my swelling seem to get worse? What advice would you give?

Asked 37 months ago by RdLlRose in Monroe, LA
Sort 5 expert answers by:
+2

Juvederm does not metastasize

Juvederm is an excellent hyaluronic acid based injectable that can be used effectively for facial contouring. Juvederm is commonly used around the lips, the smile lines, the marionette lines, under deep wrinkles, under deep scars, and even under the area of the eye. Over time, your body will help break down the Juvederm that was injected. For this reason, you may see a feeding of your result after 9 to 10 months. Juvederm however never metastasizes. When we use the word... more
B. Pat Pazmino, MD
Miami Plastic Surgeon
+2

Some factors affect Juvederm longevity

The injection techniques used are critical in creating a long term effect. Both the amount of filler injected and the layer it is injected into can be criticial in the amount of time a filler lasts. Be sure to find an experienced injector. Also be sure to recognize that most injectables are "off label" for use in the lips. I hope this helps.
Steven H. Williams, MD
San Francisco Plastic Surgeon
+1

Juvederm in the lips

The initial results you saw may have been partially from swelling. Now that you are more than a month out and seeing that the lips are not as full, you may just need more material. 
Steven Wallach, MD
Manhattan Plastic Surgeon
+1

Juvederm does not metastasize.

Hi! Just going by your description (and patients can certainly misinterpret findings), it sounds like the Juvederm was injected too deep in your upper lip, so that you have lumps on the inside and not enough improvement on the outside. Live with this for another month. If the lumps really bother you ( I assume they cannot be seen), then they can be dissolved with hyaluronidase injections. Otherwise, they will slowly disappear in the next few months. Howw a filler is injected is MUCH more... more
George J. Beraka, MD
Manhattan Plastic Surgeon
+1

Hyaluronic acid fillers in the lips do not last very long.

These fillers generally do not last very long in the lips. I don't think there is anything particularly unusual about your case. Juvederm on average can last about 3 months in the lips, but for some people, it seems to last just a little over a month in this area area of the face in which there is a significant amount of movement. I would hold the massaging at this point and consider being evaluated for the lumps inside the lips by the individual who performed your injections, though they... more
Bryan K. Chen, MD
San Diego Dermatologist
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