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BDDE in Restylane

Does the BDDE that is in restylane break down in the body?

1 Doctor Answer | Asked by Simba1234 in Sweden
+2

Safety of BDDE in Restylane

You must have read that BDDE (1,4-butanediol diglycidyl ether) may cause cancer in mice. In fact BDDE MAY have been associated with tumor formation in mice following topical application in ONE study. allow me to quote from the FDA paper Cancer Risk Assessment P020023 quoted below "Since negative results were obtained in the mutagenicity studies of Restylane, and since the estimated excess cancer risk is in the range determined to be acceptable for compounds released from... more

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