Adverse events after Botox injections received a lot of attention after the FDA mandated a "boxed warning" for both products. The patient Medication Guide lists a range of horrible things such as loss of bladder control or inability to speak; though these messages are required by the FDA, no serious adverse events related to spread of the product beyond the injection site have ever happened with cosmetic doses. This despite the millions of injections that have been done. One really has to wonder what the FDA's motives were in requiring the warning.
That said, it is wise to make sure that your injector is experienced and using the real thing. Bad things happened when some doctors bought some botulinum from a lab that normally supplies only research facilities.



