What Alternatives to Restylane Do You Recommend for Lips?

Which filler is the least painful and longest lasting for lips?

Doctor Answers 17


There is a new product from Juvederm that is specifically designed for the lips. It's called Volbella and is preferred to Juvéderm Ultra because it has a smoother, softer consistency that mimics the natural feel of your lips better. Studies have found that results lasts longer, too. 

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Alternatives to Restylane for Lips

Juvederm XC works extremely well in the lips as well. Radiesse and Sculptra are two products to generally avoid in the lips.

Kris M. Reddy, MD, FACS
West Palm Beach Plastic Surgeon
4.5 out of 5 stars 21 reviews

Juvederm Ultra for lip enhancement

I tend to use a lot of Juvederm Ultra XC for injectable lip enhancement.  It is pre-mixed with Lidocaine to make it more comfortable and tends to last around 6-9 months in my patients.  Injecting Juvederm Ultra XC in the lips through a micro-cannula also helps to reduce bruising and swelling.  It also hides the  injection sites completely.

Jason D. Bloom, MD
Philadelphia Facial Plastic Surgeon
5.0 out of 5 stars 11 reviews

Restylane - What Alternatives to Restylane Do You Recommend for Lips?


Of all the areas that undergo injection of fillers there's no question that this area - the lips - can hurt the most.  Although both recommended fillers (Restylane and Juvederm) now come with lidocaine mixed in, which definitely makes it less uncomfortable, I have a certain group of patients who prefer a nerve block to diminish the discomfort of the injections.  It's a matter of preference; it's generally up to the patient although as a physician-injector I cannot, of course, do the careful job I'd like to do if the patient is squirming.

So while I don't use nerve blocks for any facial areas aside from the lips - because it's not necessary - this is one area where I still offer it as an option.

And as far as options:  Restylane or Juvederm.  Those are the only products I would be comfortable (at this time) injecting into the lips.

I hope that this helps, and good luck,

Dr. E

Long lasting filler for fuller lips...

Juvederm Ultra XC is a great filler to use for the lips.  In general it lasts for about 6-9 months.  Now that the manufacturer has added lidocaine to the filler, the procedure is very easy and results in only little discomfort.  Another alternative that gives permanent results would be the use of medical grade silicone.  A microinjection technique is used to avoid bumps and the silicone is built up over a series of injections to create a permanent result.  Be sure to seek out a practitioner who is highly experienced in injection techniques before having the procedure done. 

Andrew Miller, MD
Edison Facial Plastic Surgeon
5.0 out of 5 stars 89 reviews

Lip Injections...

I prefer Juvederm Ultra Plus XC.  It is FDA approved to last up to 12 months, however, I always like to tell my patients it will last 6 to 9 months in the lips.  Then, if it does last longer... you, as a patient, are happy.  To help with the discomfort of the injections, I recommend my patients to come in half an hour to one hour prior to their actual treatment time for topical numbing to be put on them.  This helps significantly.  I also give a big bag of crushed ice to help in between injections.  If with all of this the patient is still uncomfortable, I will then offer a dental block.  -I rarely have to go to this measure for patient satisfaction. 

Hope this helps.

Dr. Grant Stevens

Grant Stevens, MD
Los Angeles Plastic Surgeon
4.5 out of 5 stars 77 reviews


Juvederm is the best for the lips, if you do not want restylane.  The technique and skill of the physician will help reduce the pain.

Mitchel P. Goldman, MD
San Diego Dermatologic Surgeon
4.5 out of 5 stars 7 reviews

What Alternatives to Restylane Do You Recommend for Lips?

 Both available lip fillers, Restylane and Juvederm last about the same at 4-6 months.  the other thicker fillers like Perlane, radiesse and the permanent one (Artefil) are more likely to create problems IMHO as these are meant to be injected into fat tissue which the lips have none.  If you want longer lasting lip augmentation that these temporary fillers can offer, you might want to consider lip implants of which I believe Alloderm is the most superior in the feel, look and aesthetic results.

Francis R. Palmer, III, MD
Beverly Hills Facial Plastic Surgeon
4.5 out of 5 stars 12 reviews

The best, least painful treatments for lips

Juvederm or Restylane are still the best options for correcting an aging lip. There are many tricks to minimizing the discomfort of the injections. Usually "fear of the unknown" is the worst part. The more tense you are, the more you feel. The following are my suggestions to minimize discomfort:

1. Restylane and Juvederm come pre-mixed with lidocaine, which helps.
2. I use a "dental block" which really works well to minimize discomfort.
3. "Talk-Aesthesia" to relax the patient.
4. A squeeze ball as a last resort because it will be counter-productive to tense up any part of your body.


Mitchell Schwartz, MD
South Burlington Dermatologic Surgeon
5.0 out of 5 stars 9 reviews

Options for fillers for lips

Contrary to what other suggest, there will always be a certain amount of discomfort associated with injection treatments and the degree to which one experiences pain will be individualized based upon own tolerance, threshold, and perception.  Even the use of a dental block will have its own discomfort associated with this procedure.

There are certainly good measures to help reduce discomfort such as using products with lidocaine (Restylane, Juvederm), topical numbing cream, icing, and a gentle technique.  A good injector will be mindful of wanting to keep their patient as comfortable and relaxed as possible.

With regards to duration, using the smooth HA dermal fillers are the best and safest option for mouth augmentation.  However, a handful of our patients have opted for Perlane vs. Restylane & Juvederm because they were able to experience a prolonged outcome.

Harold J. Kaplan, MD
Los Angeles Facial Plastic Surgeon
5.0 out of 5 stars 6 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.