AlloDerm Vs Strattice in Terms of Rejection Rate?

asked 2 years ago by imadvice in New York
Latest answer by Karol A. Gutowski, MD
Question viewed 4,760 times

Hello Doctors. What is your opinion on the use of Alloderm or Strattice? What are the pros and cons of each product? And its rejection rates when compared to each other?

4 answers to AlloDerm Vs Strattice in Terms of Rejection Rate?

Alloderm and Strattice are comparable and unlikely to cause rejection.

Alloderm and Strattice are products of LifeCell corporation and are acellular cadaveric (human or porcine) dermal grafts. I have used Alloderm since 1995, first in burn reconstruction, then head and neck reconstruction, during my residency. I used it briefly as a lip implant, however its most popular use is in breast cancer reconstruction where it is employed as an "inferolateral" sling to keep the breast implant or tissue expander in position as well as to "buttress"... more

Lavinia Chong, MD
Orange County Plastic Surgeon

Alloderm vs Strattice in breast reconstruction

“Rejection” of Alloderm or Strattice is generally not a problem as the immunologic components of the product are removed during processing. The more common problem is exposure of the product or infection. There have been reports of slightly more infections when Alloderm was used for breast reconstruction compared to when it was not used but other studies did not find a difference. One study found a significantly higher rate of needing to remove the expander due to infection... more

Karol A. Gutowski, MD
Chicago Plastic Surgeon

Alloderm and Strattice

I have used both products for breast reconstruction with tissue expanders/implants after mastectomy. Alloderm is human derived acellular dermal graft and Strattice is a porcine derived dermal graft. Both products are made by LifeCell. I do not feel the word "rejection" applies to these products. These products are "acellular" therefore your body should not reject them. The term to use is "incorporation." These grafts have... more

Peter Ashjian, MD
Bakersfield Plastic Surgeon

Differences between Strattice and Alloderm

Both products consist of a sheet of collagen matrix from skin with all cells removed. They act as a framework to support the ingrowth of your own tissue over time, and so they are proving very useful in breast implant surgery, both in reconstruction and revisions of augmentation. Alloderm is from donated human skin, and it has been in use for more than 10 years with an excellent safety record. It is used primarily for breast reconstruction to support implants. Strattice is a... more

Richard Baxter, MD
Seattle Plastic Surgeon

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