Is It at All Possible That Topical Minoxidil Applied to the Scalp Could Cause Systemic Side Effects Involving the Face?

I used topical minoxidil for 1yr and got results with my hair, but noticed distinct changes in my face, including dark circles & lines under my eyes and changes to skin texture. After searching online, I found dozens of people reporting the same issues (try googling "minoxidil dark circles"). The number of such reports and the fact that minoxidil is a vasodilator makes me question its safety. Is it possible to definitively say that minoxidil cannot cause systemic side effects involving the face?

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