How is Adant Different from Restylane?

asked 2 years ago by teeleck in thailand
Latest answer by Ronald Shelton, MD
Question viewed 822 times
Tags: costs, hyaluronic acid

I am considering to have filler treatment but after I searched "hyarulonic acid", I found that Adant (treatment for Osteoarthritis of the knee) is also the same ingredient with Restylane and much more cheaper so I am wonder why doctor decided to use Restylane instead of Adant. Thanks for your answers!

6 answers to How is Adant Different from Restylane?

Adant is designed to treat arthritis.

Dear Teeleck Adant is a hyaluronic acid filler designed to be injected by a physician into an arthritic joint essentially as a lubricant. The product is not approved for use in the United States. Synvisc is a hyaluronic acid filler that is used in the United States for this purpose. However, these drugs are not designed or tested for their compatiblity in the face. Fillers for facial use need to be well tolerated and they need to stay where places. Too runny and the material will... more

Kenneth D. Steinsapir, MD
Los Angeles Oculoplastic Surgeon

Using CHEAPER versions of Hyaluronic Acid

I think most would agree that the BEST fillers should be free or cheap, last forever and have NO complications. I think there are people out there who have the same demands of rich chocolate cake (free, taste great and have no calories...). Neither one exists in REAL life. A few years ago, as it became obvious that the Europeans had access to hyaluronic acid fillers (Restylane etc) while we in the US did NOT because they were still being evaluated by the FDA - several Plastic surgeons and Dermat more

Peter A. Aldea, MD
Memphis Plastic Surgeon

Restylane is FDA approved for facial injection

Simple reason: safety. Restylane has been used in millions of people safely and effectively and is FDA approved for facial lines and folds. It is hyaluronic acid that is manufactured and crossliked for this purpose. This other product is not for facial injections, and I do not think it is even crosslinked.

Mary Lupo, MD
New Orleans Dermatologist

Different formulations for different indications

Though hyaluronic acids were first formulated for the treatment of joint disease, the formulation is very much different than the ones that are used for soft tissue augmentation. Adant is used for the lubrication of arthritic knees and other joints as it is formulated chemically for such and indication. The way the molecule is formed, the structure, the bonding is completely different than your HA fillers. If the filler was injected in the dermis, who knows might develop as foreign body... more

Hassan Galadari, MD
Dubai Dermatologist

Advant is not Restylane

Chemical compounds that are similar can differ molecularly and have very different physical properties. Table sugar is not pasta but they're both carbohydrates. The thickness or viscosity, the cross binding of the molecule, the granular vs. smooth nature, molecular size, etc make the different hyaluronic acids inject differently, last differently, spread or stay localized differently, create lumpiness or hardness differently. That is why your physician would not use Advant, which is... more

Ronald Shelton, MD
Manhattan Dermatologist

www.thenyac.com

Adant and Restylane

Teeleck, Technically, Adant and Restylane are the same molecule, hyaluronic acid. This molecule is naturally found in our skin and is naturally broken down in a relatively short time period. Restylane is specially treated with a process known as crosslinking. This process makes the molecule more stable and causes it to last longer when injected. That is why your doctor recommended Restylane. He or she apparently has some integrity.

Kenneth R. Francis, MD
Manhattan Plastic Surgeon

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