I'm a male and didn't get acne until I was 25. My diet really hasn't changed (now it's super healthy). Is there a particular reason for why I got acne as a male that late? I'm on accutane now, what are the relapse rates like for adult acne?
Acne Relapse Rates for Adults After Treatment with Accutane
Doctor Answers 3
Your best chance for cure is with an aggressive initial dose
I have found that higher doses equal longer and more complete remissions. I have also found less success with each subsequent course of Accutane. I am unsure if this has been proven or published, but after 25 years of using this drug, that has been my experience.
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Depends on Dose
Let me add to Dr. Chen's well done response.
Studies have shown that the rate is higher for those who have had a lower cumulative dose per weight. Roche, when they were involved in Accutane, used to stress to us, that many physicians ( and I plead guilty) under-dosed their patients. To get full and total ablation of acne, higher cumulative doses are required.
This also means, one can use a lower dosage, but extend the duration of treatment an extra month or two ( six months rather than four).
Accutane relapse rates
Good question. I am not aware of any adult-specific relapse rate data, however, in one large study from Canada, overall, 41% of acne patients treated with isotretinoin had some degree of acne relapse, while 26% of patients required a second course of isotretinoin. Males younger than 16 had a greater rate of acne relapse than adults. Regardless, there is a good chance that you will not relapse and if you do, the acne that returns is extremely unlikely to be as bad as it was prior to starting accutane.
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