Cosmoderm is a filler derived from human tissue (foreskins from circumcisions). Zyderm, the pioneer of facial injectables, was derived from bovine collagen (leather). An advantage of Cosmoderm is that, unlike Zyderm, it does not require an allergy test.
Many physicians, including myself, find it very helpful to use around the vermilion border, the area between the lip and skin. I also like it in the crow's feet area and scars.
It does not last as long and is a bit less forgiving. Unlike the hyaluronic acid fillers (Juvederm, Restylane) once it is in cannot be recalled with something like hyaluronidase which can dissolve any mistakes. However, any beading or problems I have had with this or its predecessor, lasts for only a couple of weeks at the most.
