How Long Will a Vial of Botox Last?

I have heard varying information regarding how long a vial of Botox lasts after it is reconsituted with saline. I know the manufacturers say use within 4 hours, I have heard use within 2 weeks and also even longer. Does anyone know or tried using the Botox after different lengths of time?

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4 Doctor Answers | Asked by Mixibunny in Florida

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Allergan advises to freeze Botox until reconstituted and use within 4 hours

Dear Mixibunny Allergan, the maker of BOTOX continues to advise doctors to keep BOTOX frozen or very cold until reconstituted and then use the product with in 4 hours. In busy offices this is not a problem. However, some offices do not use the reconstituted product this rapidly. One still sees offices that have "BOTOX days" for this reason. However, about 10 years ago, Allergan leveled with the medical community and reported that their own research indicated that reconstituted... more

Kenneth D. Steinsapir, MD

8 reviews

Los Angeles Oculoplastic Surgeon

Period of Efficacy of Botox Vial

It depends on how the Botox is reconstituted. If preservative-free saline is used, then it does have to be used within a few hours. If bacteriostatic saline is used, then the Botox will last 2 weeks or longer.

Botox Longevity After Reconstitution

Hi Mixibunny, In the early days of Botox use, we scheduled "Botox days" so that we could use the mixed Botox within the four to eight hours. As time went on, many practioners have found that when refrigerated, Botox remained effective for much longer time periods. Now that Botox injections are so popular, most practioners seldom have mixed Botox around for more than a few days. Beyond two weeks on the shelve, you may want to consider treating your mother in-law with the... more

Michael A. Persky, MD

21 reviews

Los Angeles Facial Plastic Surgeon

drpersky.com

Botox is used up within a few days by most doctors

A Dr. James Fulton did a study many yrs ago that showed that Botox was still effective after 30 days, but most doctors use it up in a short time within a few days since so many patients get it now. We can go through a few bottles a day now in no time. We charge $300, 500 or 675 for 1, 2, or 3 areas.