Might wait for cryolipolysis

Arnold R. Oppenheim, MD answers: Should I wait for Liposonix to get rid of cellulite?

saw a New York Times story ("Cottage-Cheese Smoothie?") from 2006 that said cellulite laser treatment was all that works for getting rid of cellulite. They mention a radio-frequency laser named LipoSonix. Is this worth waiting for this? How long before I can get LipoSonix?


Arnold R. Oppenheim, MD
7 months ago

 I echo many of my colleagues skepticism regarding present methods for getting rid of cellulite. Some might work slightly, not nearly as well as the marketing hype would indicate, but are hardly worth the money.

    As you probably know Liposonix has not been cleared by the FDA. This machine uses ultrasound technology and maybe it will be better than its superiors in treating cellulite. The company was acquired by Medicis and if/when approved expect it to be marketed with Reloxin and Restylane. 

    You might pay attention to the work of Dr. Rox Anderson, Professor of Dermatology at Harvard. Dr. Anderson is head of research at the Wellman Center for Photomedicine at the illustrious Massachusetts General Hospital, is  probably the leading figure in laser research. He and his colleagues are working on some fascinating research on the noninvasive selective coolilng of subcutaneous fat. If this technology is fruitful it will eliminate saddle bags, love handles, back fat and most importantly cellulite. 

   Cryolipolysis crystallizes the lipids in fat cells when temperatures are above the freezing point of water. Dr. Anderson has developed a device for controlled energy extraction that is applied to the skin surface to accomplish this.  This causes the fat cells to die but the surrounding cells are uneffected. 

    Studies are showing that a cryolipolysis session lasting an hour or less results in a low-grade inflammatory process that continues for 3 months,during which fat cells are engulfed and digested by inflammatory cells and a dermal scarring response occurs.

      Studies in a multicenter clinical trial using this technology are on-going. 

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