Fluid retention is a normal reaction

Jonathan Hoenig, MD answers: Restylane side effects - Can Restylane be combined with other fillers to lessen side effects?

are there cases of severe swelling after Restylane treatment? what will the effect/s be if i will combine restylane with other Hyloronic filler?


Jonathan Hoenig, MD
15 months ago

Restylane (and other hyaluronic acid fillers) work in 2 ways:

  1. They fill the area with the actual volume that is injected.
  2. They absorb fluid to create even more fullness.

If you have severe swelling after Restylane injections, it is remotely possible that you have a true allergy to the Restylane.

More likely is that the Restylane is absorbing fluid and giving you more fullness in addition to the actual volume that was injected. You will be more susceptible to this under the eyes where the thin eyelid skin does not conceal swelling.

When I inject Restylane, especially under the eyes, I under-correct due to this tendency to absorb fluid. Then, after 2 weeks, if you still need more, we can always add more.

Juvederm tends to cause more swelling than Restylane, possibly because of the stronger cross-linking.

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