This is why most experienced board-certified dermatologists and plastic surgeons are not excited about Radiesse injection in the tear trough areas or vermilion lips. Radiesse is made of calcium hydroxyapatite complex which is an excellent filler that is longer lasting than hyaluronic acid and a good candidate filler for nasolabial folds. However, it can be quite inflammatory particularly when it is injected near bony structure of the face. Unlike hyaluronic acid which can be reversed by hyaluronidase, there is no antidote to reverse Radiesse injection. Unfortunately, there is very little you can do other than time and ice compress given the location. If it is away from the eyes, an experienced physician may consider combination of steroid and 5-flurouracil intralesional injection.


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