Mohs for DFSP

Yes.  It is the gold standard as these neoplasms can involve the margins with standard excisions. Many Mohs surgeons often excise an additional layer of skin around the negative frozen section Mohs defect and submit it to a dermatopathology laboratory for permanent section analysis. Special stains may be performed to see if there are any residual cells at the margin. Some may even do these stains in their Mohs labs on frozen sections but they may be of the minority of Mohs surgeons. When Mohs is not possible, a wide excision is necessary involving many stepsections performed by the pathologist to determine margin clearance.