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How to Tell Madelung from Regular Lipoma?

I am 41 yo male. I workout, eat well and do drink wine quite often. My dad had madelung disease but never knew how he handled it.

I started getting Lipomas 8 months ago along with a gain of 30 lbs in weight. It was after getting off Cymbalta. I now have 6 Lipomas, some tender when touched, others not. I am concerned that they could get big. The doctor said it's limpoma, but how can they know it's not Madelung? Not sure what to do. Any help? Cheers.

Asked 28 months ago by serene in denver
Sort 3 expert answers by:
+1

Lipoma or Madelung's?

It will probably be in your best interest to have the symptomatic lesions excised and evaluated pathologically. If this is done by a well experienced pathologists, he/she may be able to differentiate lipoma from the cutaneous lesions associated with benign symmetrical lipomatosis (Madelung's). Best wishes.
Tom J. Pousti, MD
San Diego Plastic Surgeon
+1

Madelung's Not True Lipomas

Madulung's Disease or Benign Symmetric Lipomatosis does not consist of true lipomas. When I perused my pathology tomes, including those devoted to Soft Tissue Pathology, Madulung's was not listed as a form of lipomas but as a lipomatosis. Experts regard it more as a metabolic condition rather than true tumors. The fatty tissue in Madelung's is not enclosed within a capsule like lipomas. Lipomas have discrete borders, small ones can be "shelled out" in a simple office... more
Arnold R. Oppenheim, MD
Virginia Beach Dermatologist
+1

Determining whether Madelung or regular Lipoma needs examination

GREAT QUESTION. Hard to tell without an examination. Madelung's disease (aka multiple symmetrical lipomatosis, cephalothoracic lipodystrophy, and the Launois-Bensaude syndrome) frequently appears in association with alcoholic liver disease, "low blood" count with fewer but big red blood cells and disorders of the peripheral nervous system. It has been associated with alcoholism. FROM http://emedicine.medscape.com/article/1057855-overview : Diffuse congenital lipomatosis Diffuse... more
Peter A. Aldea, MD
Memphis Plastic Surgeon
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