Injectable fillers are mostly FDA approved for naso-labial lines and folds. However, they are use to make great cheeks. I actually use more fillers for cheeks than lines and folds. Using a filler such as Juvederm, Restylane, Radiesse or Sculptra, cheeks can be made more youthful. This will help reduce hollow, sunken cheeks that are a sign of aging. They can also restore once fabulous cheekbones that no longer have any soft tissue over them. Which filler depends on need, cost and recovery time.
By filling cheeks, nasolabial folds are raised up and out for overall more youthful facial contour. Of course each patient needs to be treated as an individual, but I have found that even if the problem is "just" nasolabial folds, filling the cheeks as well creates a more natural, youthful result.