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Why Wouldn't Hyaluronidase Work for Dissolving Juvederm?

asked 2 years ago by anon
Latest answer by Richard H. Tholen, MD, FACS
Question viewed 1,840 times
Tags: smile, dissolve, upper lip

I've have had 2 series of injections to remove Juvederm around the corners of my mouth and have gone to 2 separate plastic surgeons to do this. It dissolved some above the upper lip where it wasn't supposed to, but nothing where it needed to. There are still palpable and visible lumps and columns of juvederm around my smile. I never looked this strange before. Is it common to take several tries and would it be risky for me to have hyaluronidase injected again in the same places?

Read my review "Loose Skin Around Mouth After Juvederm in Lips - Philadelphia, PA"

3 answers to Why Wouldn't Hyaluronidase Work for Dissolving Juvederm?

+1

Hyaluronidase does not dissolve Juvederm as much as it does naturally-occurring hyaluronic acid in tisssues!

Hyaluronidase (Wydase) is an enzyme that helps to break down Hylauronic Acid, which is what the HA fillers Restylane and Juvederm are made of. It's also a normal part of human tissues. Unfortunately, when too much HA filler is injected, or when it is injected in areas where we really didn't want it, or migrates with massage or excessive facial activity, too many doctors simply think Wydase is a simple "antidote," and seek to "break down" the offending filler by... more
Richard H. Tholen, MD, FACS

Minneapolis Plastic Surgeon
+1

Knowing what is the problem

Like Dr. Taban suggested, it may be that the Juvederm did dissolve but, in doing so, left areas that weren't filled any longer which may lend to an undesirable outcome. Another possibility is that the correct amount of hyaluronidase was not used. Technique as it pertains to amount and placement is important when dissolving with hyaluronidase. If done correctly with patience and gentle manipulation, the end benefits are usually immediate if not within 24 hours.
Harold J. Kaplan, MD

Los Angeles Facial Plastic Surgeon
+1

Hyaluronidase

Hyaluronidase will dissolve any Juvederm present, if injected in correct amount. There is no known risk to your health. The two folds in the corner of your mouth appear to be folds, and not Juvederm; hence, hyaluronidase is not working. Another reason might be if there is scar tissue present. Good luck.
Mehryar (Ray) Taban, MD, FACS

Los Angeles Oculoplastic Surgeon

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