Did Hyaluronidase cause allergic reaction?

One of the most common side effects to Hyaluronidase injections is an allergic reaction. In general, Hyaluronidase purchased from a manufacturer is less prone to causing an allergic reaction than Hyaluronidase purchased at a compounding pharmacy (when the pharmacist prepares the compound at the pharmacy). If it is an allergic reaction, you could resolve the issue by taking Benedryl or a a steroid.

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I had restylane injected into the naso-labial lines, but the needle was aimed upwards and it went into the lower part of my cheek on the right hand side, making my face feel tight when I smiled. I went back to have hyaluronidase injected into the lower right cheek and immediately got a swelling, which felt like an allergic reaction. My 'mistake' was to place ice on the swollen area, as this moved the swelling up into my eye socket, the next day when I woke up my eye and face were swollen, but I put a cool fan in the direction of my face for a few hours and over the course of the day, the swelling reduced. A day later my face was back to normal and the restylane in the lower part of my right cheek had been reduced. I think the eye area, where some people have restylane injected, make take a little longer to return to normal, after the hyaluronidase allergic reaction. I only wish the possible effects of the hyaluronidase had been explained to me from the outset, which would have saved a lot of panic.

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