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Hyaluronidase injection

What it is: Hyaluronidase injection is a treatment to correct, or lessen the effects of a dermal filler treatment containing hyaluronic acid.  If the patient is dissatisfied with the look of a dermal filler, the enzyme in a hyaluronidase injection will break it down and decrease its visible effects.

What it addresses:  Unwanted effects of hyaluronic acid dermal fillers, including:

- Juvederm
- Perlane
- Elevess
- Prevelle Silk

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Question

Did Hyaluronidase to dissolve Restylane cause allergic reaction?

I had an injection of Hyaluronidase (i think). It was an injection to dissolve some restylane that I was not happy with. I now have what looks like a blister where the Hyaluronidase was injected. The blister has gotten larger over the course of several hours. Is this an allergic reaction? When will it go away?

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Asked by: LALA LADY
LA

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1
September 18, 2008

Hyaluronidase Injection: Allergic Reaction is a Common Side Effect

Usha Rajagopal, MD
Usha Rajagopal, MD
Board Certified
Plastic Surgeon

One of the most common side effects to Hyaluronidase injections is an allergic reaction. In general, Hyaluronidase purchased from a manufacturer is less prone to causing an allergic reaction than Hyaluronidase purchased at a compounding pharmacy (when the pharmacist prepares the compound at the pharmacy).

If it is an allergic reaction, you could resolve the issue by taking Benedryl or a a steroid.

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