It is generally safe to undergo while you still have botox and fillers in place. However, this based on the presumption that these are approved and well known fillers. In some cases patients have had permanent fillers such as silicone in the face and it has compromised their blood supply to some degree and has distorted the normal anatomy of tissues. This can become a challenging facelift for you as a patient in terms of poor healing and for the surgeon in terms of achieving the desired result.
If you have had well known FDA approved fillers like Juvederm, Restylane then it should be no problem.
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