Units count Not dilution

Arnold R. Oppenheim, MD answers: Does Botox concentration vary from doctor to doctor?

I read that Botox is purchased by doctors in a powder form. And that the Botox is diluted such that one doctor may give lower concentration botox then another.  If this is true, how can i be sure that the doctor doesnt dilute my treatment more than it should be?


Arnold R. Oppenheim, MD
8 months ago

Botox comes in an  airless vial with  a film on the sides (the Botox)> It is then reconstituted by the physician or nurse. The dilution is placed into the vial and can very between 1-10 cc. Obviously the 10 cc product is 1/10th as strong as the 1 cc product. However, they equalize out when it is injection time. The physician using 10 cc dilution is going to put in 10 times as much as the physician uising the 1 cc dilution when he is putting in say 5 units,.

      I attended an advanced Botox course about 2 years ago. One skilled physician used the 10 cc dilution and the patient was left with large blobs where the Botox went. I asm sure the patient got an excellent result. The other physician used the dilutions I use, which varies depening on the area. The patient had only small bumps. I am sure his patient got equally good results.

Personally, I like to use a more dilute Botox in areas where I want diffusion (forehead, crow's feet )and more concentrated Botox in areas I want precision (glabella, lateral brow lift, DAO).

     What might be important is to be sure that the Botox is from Allergan. For awhile Allergan was encouraging us to show the patient the hologram on the vial. If you are picky you might ask to see the invoice from Allergan to ensure that the Botox came through normal Allergan channels. I would be a bit worried otherwise even if it was an Allergan vial. ( Perhaps, the vial sat on a dock someplace at room temperature and then was refrozen. I doubt whether there would be harm, but the Botox might not work.

         In sum, dilutions and amount of Botox is not the issue but units. Thinking of it, its not even that, but your results.

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