Are there different grades and potency of Botox?

A doctor that I had used for Botox recently retired. The 2 doctors that I have visited since have injected the same amount with much less effect.

Also, when being injected, the Botox solution causes a very painful contraction/cramp in the tissue it is being injected into. Can Botox be diluted? What is it being diluted with? Thanks.

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10 answers to “Are there different grades and...”

A: Questions about Botox

Ronald Shelton, MD

Botox is diluted always as it comes in a powder. The physician dilutes it with sterile saline (salt water). Painful contraction and cramping is extremely rare. The amount of saline used to dilute the Botulinum Toxin is different amongst physicians. The dose, or number of units given, is the important variable ... more

A: botox, facial contouring, Dysport

Trevor M. Born, MD

Dear Sugardonut, The amount of BOTOX is important for the overall effect and the length of effect. Also, There are 2 toxins available now- Dysport and BOTOX  Cosmetic- they require different amounts of toxin for effect. Also, very important is the agent used to dilute the BOTOX- "NON- preserved... more

A: Botox Dilution

Christopher L. Hess, MD

Botox is delivered as a freeze dried toxin that must be reconstituted with saline in order to be injected.  Practitioners can dilute the toxin any way they want.  I and many other use 2cc of saline so that each .1cc has 5 units of toxin.  But regardless you should be paying for the number of... more

A: Always diluted

Arnold R. Oppenheim, MD

   Botox come in a 100 unit vial with a film on the surface. Physicians will then dilute according to their particular preference. Many prefer to use more than one dilution ( I do). As mentioned on previous real self posts, the dilution is not as important in the ultimate result as the number of... more

A: Botox

Steven Wallach, MD

Botox is a brand name for one form of botulinum toxin.  If Botox is being injected, it is the same material.  There are other forms of toxin including that provided in Dysport.

A: Botox is Botox, but doctors may vary

Mary Lupo, MD

Botox is the brand name for a safe, highly purified botulinum toxin type A that is FDA approved for glabellar frown lines. The dilution of the 100 unit vial is the docotr's preference. What makes the differences is the number of units and where it is injected, not dilution or volume. Talk to your doctor to get... more

A: BOTOX strength

Kenneth D. Steinsapir, MD

Dear Location 98004,  It is important that you are aware of what works for you. Unfortunately not every office is honest about how much BOTOX you are getting in a syringe. The product comes dry in the vial and then is reconstituted by the doctor. Typically office use 2.5 to 4 milliliters of saline to... more

A: Botox Injection Techniques

Tanveer Janjua, MD

Botox can give variable results with different dilutions and techniques. If you used to get good result with less pain, then mention it to your physician. She/He should be able to modify the technique to cause less pain and good results. Here is a summary of dosage by units that I use for Botox or... more

A: Botox is a name brand product of the Allergan company for Botulinum Toxin type A

Steven J. Pearlman, MD

Botox is a single product that comes freeze dried from the Allergan company. Each physician chooses to dilute it according to their training and experience. It is not the dilution, but the number of units (plus the skill of the doctor) that really determines effectiveness. As for burning, this is unusual, but... more

A: Botox potency and injection diluent.

Otto Joseph Placik, MD

Ceertainly the botox can be diluted and that can vary from one physician to another. In regards to the pain, this can be related to the diluent. Package inserts recommend unpreserved saline which can actually sting more than preserved saline.

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