Are There Different Grades and Potency of Botox?
- Asked by Sugardoughnut in 98004
- 4 years ago
A doctor that I had used for Botox recently retired. The 2 doctors that I have visited since have injected the same amount with much less effect.
Also, when being injected, the Botox solution causes a very painful contraction/cramp in the tissue it is being injected into. Can Botox be diluted? What is it being diluted with? Thanks.
Standard dilution and technique of Botox injections
A unit of botox is not a unit of measurement but a unit of efficacy. The standard recommended dilution is 2.5 cc of saline per 100 unit vial. This will yield 4 unit of botox per.1cc. Ask how it is prepared and how fresh the mixture is. Botox will lose some of its effectiveness after one week.
Are there different "grades" of Botox?
Hi Sugardoughnut. While there are not two different grades of Botox, there are alternative dilutions. Botox comes to your practitioner in a vial that contains 100 "units" of Botox powder. This powder is then mixed with saline solution according to your injector's preferences. Some injectors mix the product with more saline, some with less.
Although we cannot explain the cramp you are speaking about, we will speak to the effectiveness. One of a couple things could be happening.
- Either the second and third injectors are not very skilled and are not getting the product to the right place in the muscle tissue and therefore the results are poor.
- The second and third injectors may also be using less overall "units" of Botox and this could be causing you to lose your results more quickly than with the original injector.
We would recommend that you request your medical records from your initial injector to find out what was injected (number of units) and then also request the medical records from your new injectors to compare. If the number of units is the same, then there is a technique issue. If the number of units is lower with the second and third injectors, it may just be an issue of not getting enough product. Good luck.
Questions about Botox
Botox is diluted always as it comes in a powder. The physician dilutes it with sterile saline (salt water). Painful contraction and cramping is extremely rare. The amount of saline used to dilute the Botulinum Toxin is different amongst physicians. The dose, or number of units given, is the important variable . Make sure you are comparing units per zone rather than amount of liquid.
Web reference: http://www.theynac.com
Botox, facial contouring, Dysport
Dear Sugardonut, The amount of BOTOX is important for the overall effect and the length of effect. Also, There are 2 toxins available now- Dysport and BOTOX Cosmetic- they require different amounts of toxin for effect.
Also, very important is the agent used to dilute the BOTOX- "NON- preserved saline" has as little alcohol in it and it is much les painful for the injection of the BOTOX.
Finally, the needles need to be fresh- i use a different needle for each site- a BD 31 gauge needle- very sharp so it hurts less.
With Warm Regards,
Trevor M Born MD
Botox is delivered as a freeze dried toxin that must be reconstituted with saline in order to be injected. Practitioners can dilute the toxin any way they want. I and many other use 2cc of saline so that each .1cc has 5 units of toxin. But regardless you should be paying for the number of units and this would give you an idea of what the surgeon is doing.
Botox come in a 100 unit vial with a film on the surface. Physicians will then dilute according to their particular preference. Many prefer to use more than one dilution ( I do). As mentioned on previous real self posts, the dilution is not as important in the ultimate result as the number of units in a given area and proper placement. Peoples musculature varies, most likely your original physician had your musculature down pat. Maybe, his technique was better. Its hard to tell.
Botox is a brand name for one form of botulinum toxin. If Botox is being injected, it is the same material. There are other forms of toxin including that provided in Dysport.
Botox is Botox, but doctors may vary
Botox is the brand name for a safe, highly purified botulinum toxin type A that is FDA approved for glabellar frown lines. The dilution of the 100 unit vial is the docotr's preference. What makes the differences is the number of units and where it is injected, not dilution or volume. Talk to your doctor to get that information. Cramping often means very diluted Botox that requires more volume to get an effect.
Dear Location 98004,
Web reference: http://lidlift.com/botox/
Botox Injection Techniques
Botox can give variable results with different dilutions and techniques. If you used to get good result with less pain, then mention it to your physician. She/He should be able to modify the technique to cause less pain and good results.
Here is a summary of dosage by units that I use for Botox or Dysport:
Glabella 20units botox, 50units dysport
Crows feet 20units botox, 50 units dysport
Forehead 20units botox, 50 units dysport
I use 30 gauge needle which is very small and ask patients to apply Emla cream one hour before injections.
Web reference: http://www.janjuafacialsurgery.com
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.