Could Increase dosage

Arnold R. Oppenheim, MD answers: Is it safe to increase Accutane dosage?

I've been for 2 months on Roaccutan (Accutane) and unfortunately, I can't see any improvement. My daily dose is 30 mg and I weigh 72 kilos (158 lbs). Is the dose enough or should I go higher? When am I supposed to see improvement? Thanks.


Arnold R. Oppenheim, MD
2 months ago

  In treating acne patients with Accutane, my approach isery similar to Dr. Chen's. I begin with a relativly small dosage, roughly0.5mg./kg. If a patient is doing well, without side effects and the blood work is coming back as normal, I then increase the dosage to 1 mg/kg or so. If the patient is getting a good response, and there are no problems, I will add an extra month of treatment. Your proposed dosage of 60 mg. is certainly quite acceptable.

     Most side effects happe in the first two months. So I am fairly confidant that my patient will not have a serious side effect with the higher dose.

    Yor dermatologist would be able to follow your blood work, so it obviously would be up to them whether you could tolerate the higher dose.

   

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