Steapyrium Chloride and Lapyrium Chloride are white to light cream-colored powders. In cosmetics and personal care-products, these ingredients are used in hair preparations, including shampoos, as well as in skin care and skin-cleansing preparations.
The safety of Steapyrium Chloride, along with Lapyrium Chloride, has been assessed by the
Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel concluded that Steapyrium Chloride and Lapyrium Chloride are safe as cosmetic ingredients. In 2007, as part of the scheduled re-evaluation of ingredients, the CIR Expert Panel considered available new data on Steapyrium Chloride and Lapyrium Chloride and reaffirmed the above conclusion.CIR Safety Review: Because of the similarity between the structure of Lapyrium Chloride and the structure of Steapyrium Chloride, the CIR Expert Panel relied on data from both materials in their safety evaluation. Only a very slight dermal irritation was produced on abraded or intact skin. A 50% solution of Lapyrium Chloride produced slight to moderate erythema (redness) under occluded conditions. Steapyrium Chloride produced very slight ocular irritation under the test conditions. Steapyrium Chloride was nonmutagenic when tested in a
Salmonella/microsome assay, both with and without activation.
Steapyrium Chloride was neither an irritant nor sensitizer when tested at 100% in a repeat insult occluded patch. Steapyrium Chloride does not absorb light in the UVA or UVB range and, therefore, would not be expected to be a phototoxic agent.
Steapyrium Chloride and Lapyrium Chloride may be used in cosmetics and personal care products marketed in Europe according to the
general provisions of the Cosmetics Directive of the European Union. Ingredients of animal origin must comply with European Union animal by-products regulations.
Link to the EU Cosmetics Directive:
http://ec.europa.eu/enterprise/cosmetics/html/consolidated_d...