Cocamide MEA is derived from the fatty acids from coconut oil and monoethanolamine (MEA). In cosmetics and personal care products, Cocamide MEA is used in the formulation of bath soaps and shampoo.
The safety of Cocamide MEA has been assessed by the
Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and concluded that Cocamide MEA was safe for use in rinse-off products and safe at concentrations up to 10% in leave-on products.CIR Safety Review: The CIR Expert Panel considered data from previous safety assessments of Coconut Oil and its derivatives, Monoethanolamine (MEA),
Cocamide DEA (Diethanolamine), Stearamide DEA and MEA, Isostearamide DEA and MEA, and
Myristamide DEA and MEA in the evaluation of Cocamide MEA. These data suggested little acute, short-term, or chronic toxicity associated with dermal application. The CIR Expert Panel noted that MEA vapor was highly toxic but did not consider this significant since there was no vapor that arises from Cocamide MEA. The CIR Expert Panel noted that, unlike DEA, MEA has not been found to form a stable nitrosamine. However, MEA can react with an aldehyde to form DEA, which then can be nitrosated. Dermal application of Cocamide MEA at concentrations of 50% was nonirritating to only mildly irritating tests. Cocamide MEA was negative for mutagenicity in bacteria. In clinical tests, Cocamide MEA at a concentration of 50% was not irritating in a single-insult patch test.
More information about
nitrosamines.
Cocamide MEA may be used in cosmetics and personal care products marketed in Europe according to the
general provisions of the Cosmetics Directive of the European Union.
Link to the EU Cosmetics Directive:
http://ec.europa.eu/enterprise/cosmetics/html/consolidated_d...