Bioalcamid is a permanent filler made from 96% water and 4% syntheric polymer (poly-alkyl-imide).  Bioalcamid is designed to stimulate collagen growth which forms round the filler.

According to the manufacturer, "Bio-Alcamid serves facial lipoatrophy (facial-wasting), a severe and destructive side-effect which can be a result of antiretroviral drugs used in HIV therapy."

Bio-alcamid is used "off label" for plumping skin, facial folds, and wrinkles