Latisse is a prescription drug currently promoted by spokesmodel Brooke Shields that is applied to the base of eyelashes to generate longer lashes. Latisse keeps hairs in their growth phase, producing longer, darker and thicker eyelashes. Latisse is a lower concentration of the drug Lumigan. Average cost of Latisse is $130. Latisse eyelash lengthening is not permanent. Possible side-effects include discoloration of the eye or eyelid.